Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | CCR6 | P51684 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.51 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RGS4 | P49798 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 4/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL149927 | 0.98 | MAPT (0.53) | MAPTALDH1A1NPSR1GAACCR6 | |
| SCHEMBL10996746 | 0.80 | MAPT (0.41) | MAPTALDH1A1NPSR1GAACCR6 | |
| SCHEMBL10994041 | 0.80 | RGS4 (0.53) | MAPTALDH1A1NPSR1GAACCR6 | |
| SCHEMBL7039010 | 0.79 | MAPT (0.53) | MAPTALDH1A1HPGDCACNA1BAPBA1 | |
| SCHEMBL23565762 | 0.78 | MAOA (0.42) | MAPTALDH1A1NPSR1GAACCR6 | |
| SCHEMBL28901342 | 0.78 | MAOA (0.42) | MAPTALDH1A1NPSR1GAACCR6 | |
| SCHEMBL4974025 | 0.78 | MAOA (0.42) | MAPTALDH1A1NPSR1GAACCR6 | |
| SCHEMBL6003729 | 0.78 | SIGMAR1 (0.38) | MAPTALDH1A1NPSR1GAACCR6 | |
| SCHEMBL8569835 | 0.77 | MAPT (0.49) | MAPTALDH1A1NPSR1GAACCR6 | |
| SCHEMBL6003662 | 0.77 | PGR (0.46) | MAPTALDH1A1GAAHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0723980-B1 | Thermoplastic moulding materials with improved thermostability | BAYER AG (DE) | 1998-09-02 | — | — | EP | claimed |
| JP-8239427-A | — | — | None | — | — | JP | disclosed |
| CN-111989366-B | ABS moulding compositions with high heat resistance | 英力士苯领集团股份公司 | 2023-08-29 | — | — | CN | disclosed |
| US-11603464-B2 | High heat resistant ABS molding composition | INEOS STYROLUTION GROUP GMBH (DE) | 2023-03-14 | — | — | US | disclosed |
| US-20210108069-A1 | HIGH HEAT RESISTANT ABS MOLDING COMPOSITION | INEOS STYROLUTION GROUP GMBH (DE) | 2021-04-15 | — | — | US | disclosed |
| EP-3752561-A1 | HIGH HEAT RESISTANT ABS MOLDING COMPOSITION | INEOS Styrolution Group GmbH (DE) | 2020-12-23 | — | — | EP | disclosed |
| CN-111989366-A | ABS moulding compositions having high heat resistance | 英力士苯领集团股份公司 | 2020-11-24 | — | — | CN | disclosed |
| WO-2019158564-A1 | HIGH HEAT RESISTANT ABS MOLDING COMPOSITION | INEOS STYROLUTION GROUP GMBH (DE) | 2019-08-22 | — | — | WO | disclosed |
| US-5726265-A | N-(2-ETHYL-6-METHYL)PHENYLMALEIMIDE-ACRYLONITRILE-STYRENE TERPOLYMER | BAYER AKTIENGESELLSCHAFT (DE) | 1998-03-10 | — | — | US | disclosed |
| US-5714541-A | A MOLDING MATERIALS BLEND COMPRISING A GRAFT RUBBER AND A COPOLYMER FORMED FROM N-(2-ETHYL-6-METHYL)PHENYLMALEIMIDE WITH TWO OR MORE MONOMERS, I.E., STYRENE, ACRYLONITRILE, METHYL METHACRYLATE, ALPHA-METHYLSTYRENE; NONDISCOLORING | BAYER AKTIENGESELLSCHAFT (DE) | 1998-02-03 | — | — | US | disclosed |
| JP-H08239427-A | PLASTIC HAVING HIGH HEAT DEFLECTION TEMPERATURE AND IMPROVED HEAT STABILITY | BAYER AG | 1996-09-17 | — | — | JP | disclosed |