Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1554441 | 0.89 | PDE4A (0.42) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL1553545 | 0.87 | PDE4A (0.41) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL8571803 | 0.84 | PDE4A (0.42) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL8574183 | 0.79 | HSD17B10 (0.39) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL1553974 | 0.79 | PDE4A (0.38) | LMNA | |
| SCHEMBL8569941 | 0.77 | PDE4A (0.54) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL1553667 | 0.77 | MLKL (0.40) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL1552129 | 0.77 | PDE4A (0.39) | POLBKDM4ECYP3A4TSHR | |
| SCHEMBL1553662 | 0.76 | KDM4C (0.38) | MEN1KMT2AKDM4EALDH1A1CDC25B | |
| SCHEMBL1553472 | 0.76 | PDE4A (0.39) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |