Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.54 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1553518 | 0.90 | PDE4A (0.59) | PDE4APDE4BPDE4CPDE4DMMP2 | |
| SCHEMBL1553391 | 0.88 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4DMMP2 | |
| Hydrochloric Acid SCHEMBL8571356 | 0.86 | PDE4A (0.57) | PDE4APDE4BPDE4CPDE4DMMP2 | |
| SCHEMBL8571347 | 0.85 | PDE4D (0.59) | PDE4APDE4BPDE4CPDE4DMMP2 | |
| SCHEMBL1553474 | 0.82 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL8570416 | 0.81 | PDE4D (0.52) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| SCHEMBL6942891 | 0.80 | MAPT (0.47) | MEN1KMT2AMMP2SMN1; SMN2MAPT | |
| SCHEMBL1553610 | 0.79 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8570317 | 0.79 | PDE4D (0.52) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| SCHEMBL8574189 | 0.79 | PDE4A (0.52) | PDE4APDE4BPDE4CPDE4DMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |