Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.39 |
| ▸ | NTRK2 | Q16620 | 4/20 | 0.39 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.39 |
| ▸ | BRS3 | P32247 | 1/20 | 0.38 |
| ▸ | ECE1 | P42892 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8570003 | 0.93 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4DHPGD | |
| SCHEMBL8574149 | 0.89 | PDE4A (0.51) | PDE4APDE4BPDE4CPDE4DRNASEH1 | |
| SCHEMBL2524512 | 0.84 | HSD17B10 (0.42) | PDE4APDE4BPDE4CPDE4DHSD17B10 | |
| SCHEMBL1553391 | 0.83 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4DMMP2 | |
| SCHEMBL8574115 | 0.83 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DHSD17B10 | |
| SCHEMBL8569965 | 0.83 | RAB9A (0.48) | HSD17B10STING1HPGD | |
| SCHEMBL8571583 | 0.83 | SMN1; SMN2 (0.43) | HSD17B10STING1 | |
| Hydrochloric Acid SCHEMBL8571356 | 0.82 | PDE4A (0.57) | PDE4APDE4BPDE4CPDE4DMMP2 | |
| SCHEMBL1553518 | 0.81 | PDE4A (0.59) | PDE4APDE4BPDE4CPDE4DMMP2 | |
| SCHEMBL8571347 | 0.81 | PDE4D (0.59) | PDE4APDE4BPDE4CPDE4DMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |