Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8571583 | 0.91 | SMN1; SMN2 (0.43) | RAB9ASMN1; SMN2NPC1POLBROCK2 | |
| SCHEMBL8574115 | 0.87 | PDE4A (0.47) | HSD17B10KDM4EGAASTING1ALDH1A1 | |
| SCHEMBL8571546 | 0.86 | HSD17B10 (0.47) | RAB9ASMN1; SMN2NPC1POLBROCK2 | |
| SCHEMBL2524512 | 0.85 | HSD17B10 (0.42) | RAB9ANPC1LMNAMEN1KMT2A | |
| SCHEMBL1552751 | 0.84 | SMN1; SMN2 (0.50) | RAB9ASMN1; SMN2NPC1POLBROCK2 | |
| SCHEMBL8574149 | 0.84 | PDE4A (0.51) | POLBHSD17B10STING1 | |
| SCHEMBL8574189 | 0.83 | PDE4A (0.52) | HSD17B10STING1HPGD | |
| Hydrochloric Acid SCHEMBL8568583 | 0.83 | SMN1; SMN2 (0.49) | RAB9ASMN1; SMN2NPC1POLBROCK2 | |
| SCHEMBL8570003 | 0.81 | PDE4A (0.46) | RAB9ANPC1POLBHPGD | |
| SCHEMBL8568575 | 0.81 | SMN1; SMN2 (0.49) | RAB9ASMN1; SMN2NPC1POLBROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |