SCHEMBL8570275

SCHEMBL8570275

NCCNC(O)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 2/20 0.45
MTOR P42345 1/20 0.45
RAB9A P51151 1/20 0.45
GRM7 Q14831 1/20 0.45
AOC3 Q16853 4/20 0.44
CYP3A4 P08684 2/20 0.43
TSHR P16473 2/20 0.43
ALOX15 P16050 1/20 0.43
HTR2A P28223 2/20 0.43
TAAR1 Q96RJ0 2/20 0.43
SLC6A4 P31645 2/20 0.42
SLC6A3 Q01959 2/20 0.42
SLC6A2 P23975 1/20 0.42
KDM4E B2RXH2 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
KIF11 P52732 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxalic Acid SCHEMBL28233563 0.93 BCAT2 (0.42) HRH1MTORRAB9AGRM7AOC3
Acetic Acid SCHEMBL27951213 0.91 MTNR1A (0.45) HRH1MTORRAB9AGRM7TSHR
SCHEMBL29650956 0.87 MTOR (0.58) HRH1MTORRAB9AGRM7AOC3
SCHEMBL11590155 0.83 MTOR (0.48) HRH1MTORRAB9AGRM7AOC3
SCHEMBL22268526 0.80 AKT1 (0.46) AOC3CYP3A4TSHRTAAR1SLC6A4
SCHEMBL11879421 0.79 AOC3 (0.58) HRH1MTORRAB9AGRM7AOC3
SCHEMBL8352681 0.78 MTOR (0.74) HRH1MTORRAB9AGRM7CYP3A4
Hydrochloric Acid SCHEMBL28410803 0.77 CYP3A4 (0.75) HRH1MTORRAB9AGRM7CYP3A4
SCHEMBL1132858 0.76 MAN2A1 (0.46) HRH1MTORRAB9AGRM7CYP3A4
SCHEMBL1132547 0.76 MAN2A1 (0.46) HRH1MTORRAB9AGRM7CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107624115-A Botulinum neurotoxin specificity capturing agent, composition, application method and manufacture method 加州理工学院 2018-01-23 CN disclosed
EP-2964624-B1 RHODAMINE COMPOUNDS AND THEIR USE AS FLUORESCENT LABELS ILLUMINA CAMBRIDGE LTD (GB) 2017-01-04 EP disclosed
EP-0951478-A1 POLYSACCHARIDE-PEPTIDE DERIVATIVES Map Medical Technologies Oy (FI) 1999-10-27 EP disclosed
WO-1998028336-A1 POLYSACCHARIDE-PEPTIDE DERIVATIVES MAP MEDICAL TECHNOLOGIES OY (FI) 1998-07-02 WO disclosed