Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAN2A1 | Q16706 | 3/20 | 0.46 |
| ▸ | MAN1B1 | Q9UKM7 | 3/20 | 0.46 |
| ▸ | MAN2B1 | O00754 | 3/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 2/20 | 0.38 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2200107 | 1.00 | MAN2A1 (0.46) | MAN2A1MAN1B1MAN2B1EPHX2HRH1 | |
| SCHEMBL1132547 | 1.00 | MAN2A1 (0.46) | MAN2A1MAN1B1MAN2B1EPHX2HRH1 | |
| SCHEMBL258306 | 0.84 | MAN2A1 (0.49) | MAN2A1MAN1B1MAN2B1EPHX2MTOR | |
| SCHEMBL11425422 | 0.81 | HRH1 (0.42) | EPHX2HRH1MTORRAB9AGRM7 | |
| SCHEMBL27668096 | 0.81 | MAN2A1 (0.46) | MAN2A1MAN1B1MAN2B1EPHX2MTOR | |
| SCHEMBL8549011 | 0.81 | RIPK1 (0.49) | MAN2A1MAN1B1MAN2B1EPHX2MTOR | |
| SCHEMBL8549178 | 0.81 | RIPK1 (0.49) | MAN2A1MAN1B1MAN2B1EPHX2MTOR | |
| SCHEMBL8545776 | 0.81 | RIPK1 (0.49) | MAN2A1MAN1B1MAN2B1EPHX2MTOR | |
| SCHEMBL4915574 | 0.79 | L3MBTL1 (0.51) | HRH1MTORRAB9AGRM7CYP3A4 | |
| SCHEMBL24505282 | 0.78 | SMN1; SMN2 (0.50) | MAN2A1MAN1B1MAN2B1EPHX2MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8299035-B2 | 10a-azalide compound having 4-membered ring structure | TAISHO PHARMACEUTUCAL CO., LTD. (JP) | 2012-10-30 | — | — | US | disclosed |
| US-20110152239-A1 | 10A-AZALIDE COMPOUND HAVING 4-MEMBERED RING STRUCTURE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2011-06-23 | — | — | US | disclosed |
| EP-2287173-A1 | 10A-AZALIDE COMPOUND HAVING 4-MEMBERED RING STRUCTURE | Taisho Pharmaceutical Co., Ltd. (JP) | 2011-02-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152239-A1 | 10A-AZALIDE COMPOUND HAVING 4-MEMBERED RING STRUCTURE | ELOVL3, ELOVL5, SCD5 | MAN2A1 4052/4885MAN1B1 1802/4885MAN2B1 3991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.