Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6348001 | 0.79 | CA2 (0.40) | — | |
| SCHEMBL26319463 | 0.77 | MLYCD (0.38) | KMT2AMLYCD | |
| SCHEMBL28449709 | 0.77 | CA2 (0.32) | — | |
| SCHEMBL21149312 | 0.77 | MLYCD (0.38) | KMT2AMLYCD | |
| SCHEMBL20907635 | 0.77 | MLYCD (0.38) | KMT2AMLYCD | |
| SCHEMBL22992228 | 0.76 | DPP4 (0.38) | FFAR2 | |
| SCHEMBL8496982 | 0.76 | DPP4 (0.38) | FFAR2 | |
| SCHEMBL24875781 | 0.75 | FFAR2 (0.33) | KMT2AMLYCDMAPTFFAR2 | |
| SCHEMBL10050949 | 0.74 | MAPT (0.32) | KMT2AMAPT | |
| SCHEMBL26665913 | 0.74 | MAPT (0.32) | KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846990-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB CO. (US) | 1998-12-08 | — | — | US | claimed |
| EP-3504212-B1 | SUBSTITUTED PYRROLIZINE COMPOUNDS AND USES THEREOF | GILEAD SCIENCES INC (US) | 2021-05-19 | — | — | EP | disclosed |
| US-5846990-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB CO. (US) | 1998-12-08 | — | — | US | disclosed |