Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.50 |
| ▸ | EGFR | P00533 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HK1 | P19367 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7593404 | 0.73 | KMT2A (0.55) | EGFRSMN1; SMN2KMT2AMEN1HSD17B10 | |
| SCHEMBL8570467 | 0.73 | L3MBTL1 (0.49) | SRCEGFRSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL16144912 | 0.71 | LMNA (0.53) | EGFRSMN1; SMN2KMT2AHSD17B10LMNA | |
| SCHEMBL6017853 | 0.71 | SMN1; SMN2 (0.53) | SRCEGFRSMN1; SMN2KMT2AHSD17B10 | |
| SCHEMBL7452201 | 0.70 | SMN1; SMN2 (0.54) | SMN1; SMN2KMT2AMEN1HSD17B10LMNA | |
| SCHEMBL8999181 | 0.68 | SRC (0.70) | SRCEGFRSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7671576 | 0.68 | KMT2A (0.49) | SRCEGFRSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8568966 | 0.68 | SMN1; SMN2 (0.44) | SMN1; SMN2KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL8998819 | 0.67 | SRC (1.00) | SRCEGFR | |
| SCHEMBL8572439 | 0.67 | MEN1 (0.50) | SRCEGFRSMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846990-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB CO. (US) | 1998-12-08 | — | — | US | disclosed |