Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30639179 | 0.73 | KDM4E (0.67) | L3MBTL1KDM4ETSHRKMT2AMEN1 | |
| SCHEMBL1092586 | 0.73 | KDM4E (0.67) | L3MBTL1KDM4ETSHRKMT2AMEN1 | |
| SCHEMBL8570462 | 0.73 | SRC (0.50) | L3MBTL1KDM4EHSD17B10SRCKMT2A | |
| SCHEMBL8574909 | 0.71 | TACR1 (0.43) | KDM4ETSHRHSD17B10KMT2AMEN1 | |
| SCHEMBL8568969 | 0.71 | TACR1 (0.40) | KDM4EKMT2AMEN1TACR1SMN1; SMN2 | |
| SCHEMBL17484805 | 0.70 | TSHR (0.66) | L3MBTL1KDM4ETSHRHSD17B10SRC | |
| SCHEMBL5883327 | 0.70 | TACR1 (0.54) | KDM4ETSHRHSD17B10KMT2AMEN1 | |
| SCHEMBL7452209 | 0.69 | TACR1 (0.46) | KMT2AMEN1TACR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL19850206 | 0.69 | ALDH1A1 (0.40) | HSD17B10SRCKMT2AMEN1PGR | |
| SCHEMBL8573164 | 0.69 | GPBAR1 (0.45) | L3MBTL1KMT2AMEN1TACR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846990-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB CO. (US) | 1998-12-08 | — | — | US | disclosed |