Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.81 |
| ▸ | MAPT | P10636 | 3/20 | 0.74 |
| ▸ | TSHR | P16473 | 2/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | GFER | P55789 | 1/20 | 0.67 |
| ▸ | DRD4 | P21917 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CASP1 | P29466 | 1/20 | 0.60 |
| ▸ | CASP4 | P49662 | 1/20 | 0.60 |
| ▸ | CASP5 | P51878 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | DRD2 | P14416 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.59 |
| ▸ | FAAH | O00519 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15938394 | 0.89 | MAPT (0.71) | SIGMAR1MAPTTSHRKDM4EALDH1A1 | |
| SCHEMBL8729399 | 0.88 | SIGMAR1 (0.67) | SIGMAR1MAPTTSHRKDM4EALDH1A1 | |
| SCHEMBL20804357 | 0.88 | SIGMAR1 (0.90) | SIGMAR1MAPTTSHRKDM4EALDH1A1 | |
| SCHEMBL28186295 | 0.88 | SIGMAR1 (0.90) | SIGMAR1MAPTTSHRKDM4EALDH1A1 | |
| SCHEMBL27903294 | 0.88 | SIGMAR1 (0.66) | SIGMAR1MAPTTSHRKDM4EALDH1A1 | |
| SCHEMBL28802676 | 0.88 | SIGMAR1 (0.66) | SIGMAR1MAPTTSHRKDM4EALDH1A1 | |
| SCHEMBL6703194 | 0.88 | SIGMAR1 (0.66) | SIGMAR1MAPTTSHRKDM4EALDH1A1 | |
| SCHEMBL15937935 | 0.84 | DRD4 (0.69) | SIGMAR1MAPTTSHRKDM4EALDH1A1 | |
| SCHEMBL11923385 | 0.84 | SIGMAR1 (0.79) | SIGMAR1MAPTTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL19212406 | 0.83 | ADRB1 (0.69) | MAPTTSHRKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998008091-A1 | NORMALIZATION OF COMBINATORIAL REACTIONS | ISIS PHARMACEUTICALS, INC. (US) | 1998-02-26 | — | — | WO | disclosed |