Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | RECQL | P46063 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4412650 | 0.85 | HPGD (0.66) | ALDH1A1MAPK1MEN1KMT2ATSHR | |
| SCHEMBL23182640 | 0.84 | MAPK1 (0.73) | ALDH1A1L3MBTL1POLBMAPK1SMN1; SMN2 | |
| Benzene SCHEMBL7861838 | 0.82 | MAPK1 (0.75) | ALDH1A1L3MBTL1POLBMAPK1SMN1; SMN2 | |
| SCHEMBL2008321 | 0.82 | MAPK1 (0.75) | ALDH1A1L3MBTL1POLBMAPK1SMN1; SMN2 | |
| SCHEMBL5717757 | 0.81 | MAPK1 (1.00) | ALDH1A1L3MBTL1POLBMAPK1SMN1; SMN2 | |
| SCHEMBL3044729 | 0.81 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1POLBMAPK1SMN1; SMN2 | |
| SCHEMBL10443548 | 0.80 | MAPK1 (0.68) | ALDH1A1L3MBTL1POLBMAPK1SMN1; SMN2 | |
| SCHEMBL8570374 | 0.80 | MAPK1 (0.71) | ALDH1A1L3MBTL1POLBMAPK1SMN1; SMN2 | |
| SCHEMBL11450079 | 0.80 | POLB (0.58) | ALDH1A1L3MBTL1POLBMAPK1SMN1; SMN2 | |
| SCHEMBL22284070 | 0.79 | ALDH1A1 (0.66) | ALDH1A1L3MBTL1POLBMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846990-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB CO. (US) | 1998-12-08 | — | — | US | claimed |