SCHEMBL4412650

SCHEMBL4412650

CN(C)C(=O)Cn1c(=O)oc2ccccc21

nearest known ligand 0.80

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.66
CDYL Q9Y232 2/20 0.64
CBX7 O95931 1/20 0.64
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
LMNA P02545 1/20 0.59
USP2 O75604 1/20 0.58
TSHR P16473 1/20 0.58
MAPK1 P28482 1/20 0.58
CDY1; CDY1B Q9Y6F8 1/20 0.58
ALDH1A1 P00352 2/20 0.58
HTT P42858 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5418563 0.89 TSPO (0.65) CDYLCBX7
SCHEMBL8570807 0.85 ALDH1A1 (0.73) MEN1KMT2ALMNATSHRMAPK1
SCHEMBL4412637 0.85 MEN1 (0.63) HPGDCDYLCBX7MEN1KMT2A
SCHEMBL13995838 0.83 HPGD (0.71) HPGDCDYLCBX7MEN1KMT2A
SCHEMBL4424971 0.81 TP53 (0.61) HPGDCDYLCBX7MEN1KMT2A
SCHEMBL2947194 0.81 HPGD (0.73) HPGDLMNAUSP2TSHRMAPK1
SCHEMBL4420217 0.80 TP53 (0.58) HPGDCDYLCBX7MEN1KMT2A
SCHEMBL4414497 0.80 TP53 (0.61) HPGDKMT2ALMNA
SCHEMBL4414345 0.80 HPGD (1.00) HPGDCDYLCBX7MEN1KMT2A
SCHEMBL10444126 0.79 ALDH1A1 (0.64) HPGDMEN1KMT2ALMNAUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8293775-B2 Benzoxazolone derivatives, processes for preparing them and their uses UCB PHARMA, S.A. (BE) 2012-10-23 US claimed
EP-1756071-B1 BENZOXAZOLONE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES UCB PHARMA SA (BE) 2009-08-26 EP claimed
US-20070299118-A1 Benzoxazolone Derivatives, Processes For Preparing Them And Their Uses UCB, S.A. (BE) 2007-12-27 US claimed
EP-1756071-A1 BENZOXAZOLONE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES UCB, S.A. (BE) 2007-02-28 EP claimed
WO-2005118561-A1 BENZOXAZOLONE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES UCB, S.A. (BE) 2005-12-15 WO claimed
US-8293775-B2 Benzoxazolone derivatives, processes for preparing them and their uses UCB PHARMA, S.A. (BE) 2012-10-23 US disclosed
EP-1756071-B1 BENZOXAZOLONE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES UCB PHARMA SA (BE) 2009-08-26 EP disclosed
US-20070299118-A1 Benzoxazolone Derivatives, Processes For Preparing Them And Their Uses UCB, S.A. (BE) 2007-12-27 US disclosed
EP-1756071-A1 BENZOXAZOLONE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES UCB, S.A. (BE) 2007-02-28 EP disclosed
WO-2005118561-A1 BENZOXAZOLONE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES UCB, S.A. (BE) 2005-12-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070299118-A1 Benzoxazolone Derivatives, Processes For Preparing Them And Their Uses PARK7, SNCA, GABRA5 HPGD 232/4885CDYL 2044/4885CBX7 334/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.