Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | DHFR | P00374 | 2/20 | 0.43 |
| ▸ | TYMS | P04818 | 3/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | RHEB | Q15382 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8564897 | 0.82 | HTR1A (0.49) | KDM4EHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL8566577 | 0.80 | HTR1A (0.42) | KDM4EHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL30688805 | 0.77 | POLB (0.56) | KDM4EHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL2282611 | 0.77 | POLB (0.56) | KDM4EHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL29543630 | 0.77 | POLB (0.56) | KDM4EHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL8566460 | 0.76 | HTR1A (0.45) | KDM4EHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL10596007 | 0.75 | POLB (0.55) | KDM4EHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL10708413 | 0.73 | POLB (0.62) | KDM4EHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL3282084 | 0.71 | POLB (0.56) | KDM4EHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL1821162 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826674-A1 | NOVEL PYRIMIDINE DERIVATIVES EFFICACIOUS AS PSYCHOTROPIC DRUG AND PROCESS FOR THE PRODUCTION THEREOF | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-03-04 | — | — | EP | disclosed |