Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | DRD4 | P21917 | 3/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8566460 | 0.83 | HTR1A (0.45) | HTR1ADRD2DRD4HPGDALDH1A1 | |
| SCHEMBL8571069 | 0.80 | KDM4E (0.45) | HPGDALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL8564591 | 0.79 | HTR1A (0.64) | HTR1ADRD2DRD4HPGDALDH1A1 | |
| SCHEMBL8566180 | 0.79 | HTR1A (0.41) | HTR1ADRD2DRD4KDM1AHPGD | |
| SCHEMBL8570726 | 0.78 | PDE4A (0.42) | HTR1ADRD2DRD4KDM1AHPGD | |
| SCHEMBL6847060 | 0.76 | CXCL12 (0.47) | KDM1AHPGDALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL17795952 | 0.76 | CXCL12 (0.52) | KDM1AHPGDALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL17302068 | 0.74 | L3MBTL1 (0.41) | HTR1ADRD2DRD4KDM1AALDH1A1 | |
| SCHEMBL1741595 | 0.74 | LMNA (0.41) | HTR1ADRD2DRD4KDM1AALDH1A1 | |
| SCHEMBL8723876 | 0.72 | HPGD (0.53) | KDM1AHPGDALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826674-A1 | NOVEL PYRIMIDINE DERIVATIVES EFFICACIOUS AS PSYCHOTROPIC DRUG AND PROCESS FOR THE PRODUCTION THEREOF | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-03-04 | — | — | EP | disclosed |