Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | G6PD | P11413 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8415998 | 0.87 | ALOX5 (0.33) | ALOX5MEN1KMT2AGAACYP1A2 | |
| SCHEMBL8683030 | 0.75 | ALOX5 (0.42) | ALOX5MEN1KMT2AGAACYP1A2 | |
| SCHEMBL11188819 | 0.73 | MEN1 (0.34) | ALOX5MEN1KMT2AGAACYP1A2 | |
| SCHEMBL4653392 | 0.72 | CYP2D6 (0.36) | MEN1KMT2AGAACYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL10834103 | 0.72 | MEN1 (0.33) | ALOX5MEN1KMT2AGAACYP1A2 | |
| SCHEMBL8417012 | 0.72 | GAA (0.43) | GAASMN1; SMN2NPSR1KDM4EALDH1A1 | |
| SCHEMBL8415370 | 0.71 | GAA (0.40) | MEN1KMT2AGAACYP1A2CYP2C9 | |
| SCHEMBL8414045 | 0.71 | TSHR (0.40) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7367469 | 0.70 | GBA1 (0.41) | SLC6A2 | |
| SCHEMBL7097242 | 0.70 | KCNA5 (0.38) | CYP2C9CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |