Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | UGCG | Q16739 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8981041 | 0.82 | HEXA (0.38) | MEN1KMT2AMAPTALDH1A1HSD17B10 | |
| SCHEMBL8575290 | 0.80 | KMT2A (0.50) | MEN1KMT2AMAPTALDH1A1ABCB1 | |
| SCHEMBL8797253 | 0.77 | RAB9A (0.41) | MAPTALDH1A1 | |
| SCHEMBL8577578 | 0.74 | CISD1 (0.39) | MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8577576 | 0.73 | MAOA (0.33) | DRD2DRD4DRD3UGCGMEN1 | |
| Hydrochloric Acid SCHEMBL9809661 | 0.73 | CYP3A4 (0.58) | DRD2DRD3MAPTABCB1 | |
| SCHEMBL6947117 | 0.73 | TSHR (0.41) | MEN1KMT2AMAPT | |
| SCHEMBL8577574 | 0.72 | PIK3CG (0.35) | DRD2DRD4DRD3UGCGMEN1 | |
| SCHEMBL8796845 | 0.72 | FFAR1 (0.49) | MEN1KMT2AMAPTALDH1A1HSD17B10 | |
| SCHEMBL23231083 | 0.72 | MEN1 (0.43) | UGCGMEN1KMT2AALPLMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5710152-A | ANTIDIABETIC, ANTILIPEMIC, AND HYPOGLYCEMIC AGENTS; DIETETICS | SS PHARMACEUTICAL CO., LTD. (JP) | 1998-01-20 | — | — | US | disclosed |
| EP-0787727-A1 | Benzoazine derivative or salt thereof and pharmaceutical composition comprising the same | SS Pharmaceutical Co., Ltd. (JP) | 1997-08-06 | — | — | EP | disclosed |