Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1552116 | 0.84 | OPRM1 (0.36) | OPRM1OPRL1OPRK1 | |
| SCHEMBL4794587 | 0.79 | AKR1C1 (0.31) | AKR1C1 | |
| SCHEMBL11700256 | 0.79 | OPRM1 (0.31) | OPRM1OPRL1OPRK1 | |
| SCHEMBL1538837 | 0.76 | OPRM1 (0.31) | OPRM1OPRL1OPRK1ALDH1A1 | |
| SCHEMBL1538677 | 0.76 | OPRM1 (0.31) | OPRM1OPRL1OPRK1ALDH1A1 | |
| SCHEMBL2786782 | 0.72 | OPRM1 (0.33) | OPRM1OPRL1OPRK1 | |
| SCHEMBL6157096 | 0.71 | AKR1C1 (0.36) | OPRM1OPRL1OPRK1AKR1C1 | |
| SCHEMBL182247 | 0.71 | OPRM1 (0.35) | OPRM1OPRL1OPRK1ALDH1A1AKR1C1 | |
| Ammonia Solution, Strong SCHEMBL7597471 | 0.70 | OPRM1 (0.34) | OPRM1OPRL1OPRK1ALDH1A1AKR1C1 | |
| SCHEMBL3365469 | 0.70 | OPRM1 (0.34) | OPRM1OPRL1OPRK1ALDH1A1AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760155-A | PREPARED FROM POLYISOCYANATE, POLYOL, SILANOL-FUNCTIONAL SILICONE INTERMEDIATE; MOISTURE CURABLE AT ROOM TEMPERATURE | AMERON INTERNATIONAL CORPORATION (US) | 1998-06-02 | — | — | US | disclosed |