Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MTTP | P55157 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8573431 | 0.91 | L3MBTL1 (0.34) | NPC1RAB9A | |
| SCHEMBL8573316 | 0.89 | TRPV1 (0.40) | NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL8573033 | 0.85 | NPC1 (0.37) | NPC1RAB9AMTTPMAPTSMN1; SMN2 | |
| SCHEMBL8574848 | 0.85 | FLT3 (0.40) | NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL8572056 | 0.84 | NR2E1 (0.33) | NPC1RAB9A | |
| SCHEMBL8574487 | 0.82 | POLB (0.32) | JAK1 | |
| SCHEMBL8573038 | 0.82 | GAA (0.42) | NPC1RAB9AMAPT | |
| SCHEMBL8573805 | 0.79 | GAA (0.41) | NPC1RAB9AMAPT | |
| SCHEMBL8573842 | 0.78 | TRPV1 (0.43) | NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL8500999 | 0.78 | CTSL (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760246-A | ANTILIPEMIC AGENTS, ANTICHOLESTEROL AGENTS | BRISTOL-MYERS SQUIBB COMPANY | 1998-06-02 | — | — | US | disclosed |