Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | UGCG | Q16739 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8573842 | 0.90 | TRPV1 (0.43) | TRPV1MAPK14PTPN1NPC1RAB9A | |
| SCHEMBL8573310 | 0.89 | NPC1 (0.38) | NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL8574848 | 0.88 | FLT3 (0.40) | TRPV1PTPN1NPC1RAB9AUGCG | |
| SCHEMBL8573431 | 0.88 | L3MBTL1 (0.34) | TRPV1NPC1RAB9AGAAHDAC3 | |
| SCHEMBL8573038 | 0.84 | GAA (0.42) | TRPV1NPC1RAB9AUGCGGAA | |
| SCHEMBL8577124 | 0.82 | NPC1 (0.34) | TRPV1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL8573805 | 0.82 | GAA (0.41) | TRPV1NPC1RAB9AUGCGGAA | |
| SCHEMBL8579070 | 0.82 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2GAAMAPT | |
| SCHEMBL8500999 | 0.80 | CTSL (0.37) | MAPK14CYP1A2 | |
| SCHEMBL8572056 | 0.80 | NR2E1 (0.33) | TRPV1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760246-A | ANTILIPEMIC AGENTS, ANTICHOLESTEROL AGENTS | BRISTOL-MYERS SQUIBB COMPANY | 1998-06-02 | — | — | US | disclosed |