Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Desaspidin SCHEMBL2732746 | 0.83 | FASN (0.51) | FASNMEN1KMT2APAK1FFAR1 | |
| Desaspidin SCHEMBL29613713 | 0.83 | FASN (0.51) | FASNMEN1KMT2APAK1FFAR1 | |
| SCHEMBL8904640 | 0.82 | FASN (0.38) | FASNFFAR1PLA2G2APLA2G5 | |
| SCHEMBL8571259 | 0.80 | FASN (0.51) | FASNFFAR1PLA2G2APLA2G5ALOX5 | |
| SCHEMBL29387296 | 0.76 | FASN (0.59) | FASNMEN1KMT2APAK1FFAR1 | |
| Desaspidin SCHEMBL28086151 | 0.75 | FASN (0.42) | FASNMEN1KMT2APAK1CYP19A1 | |
| SCHEMBL30212085 | 0.72 | FASN (0.66) | FASNMEN1KMT2APAK1ALOX5 | |
| SCHEMBL30212080 | 0.72 | FASN (0.66) | FASNMEN1KMT2APAK1ALOX5 | |
| SCHEMBL29929654 | 0.69 | FASN (1.00) | FASNMEN1KMT2APAK1FFAR1 | |
| SCHEMBL154937 | 0.69 | FASN (1.00) | FASNMEN1KMT2APAK1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807898-A | ASPIDIN, DESASPIDIN, METHYLENEBISASPIDINOL | KAPADIA GOVIND J (US) | 1998-09-15 | — | — | US | disclosed |
| US-5684035-A | NAPHTHOQUINONES | KAPADIA GOVIND J (US) | 1997-11-04 | — | — | US | disclosed |