Desaspidin

Desaspidin

SCHEMBL2732746

CCCC(=O)C1=C(O)C(C)(C)C(O)=C(Cc2c(OC)cc(O)c(C(=O)CCC)c2O)C1=O

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ FASN P49327 8/20 0.51
▸ MEN1 O00255 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ PAK1 Q13153 1/20 0.42
▸ HMGCR P04035 1/20 0.35
▸ PTGES O14684 1/20 0.35
▸ ALOX5 P09917 1/20 0.35
▸ FFAR1 O14842 1/20 0.34
▸ PLA2G2A P14555 1/20 0.34
▸ PLA2G5 P39877 1/20 0.34
▸ CYP19A1 P11511 1/20 0.34
▸ MAPT P10636 1/20 0.33
▸ SENP8 Q96LD8 1/20 0.33
▸ SENP7 Q9BQF6 1/20 0.33
▸ SENP6 Q9GZR1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Desaspidin SCHEMBL29613713 1.00 FASN (0.51) FASNMEN1KMT2APAK1HMGCR
Desaspidin SCHEMBL28086151 0.90 FASN (0.42) FASNMEN1KMT2APAK1CYP19A1
SCHEMBL29387296 0.89 FASN (0.59) FASNMEN1KMT2APAK1HMGCR
SCHEMBL30212080 0.85 FASN (0.66) FASNMEN1KMT2APAK1HMGCR
SCHEMBL30212085 0.85 FASN (0.66) FASNMEN1KMT2APAK1HMGCR
SCHEMBL8573383 0.83 FASN (0.51) FASNMEN1KMT2APAK1HMGCR
SCHEMBL4742082 0.82 FASN (0.63) FASNPTGESALOX5
SCHEMBL155672 0.80 FASN (0.48) FASN
SCHEMBL1785484 0.78 FASN (0.60) FASNPTGESALOX5PLA2G2APLA2G5
SCHEMBL4962391 0.76 FASN (0.64) FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150056160-A1 CHEMICALLY INDUCED INTRACELLULAR HYPERTHERMIA TEXAS PHARMACEUTICALS, INC. 2015-02-26 — — US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 — — CN claimed
EP-0931542-B1 Cosmetic composition containing phloroglucinol OREAL (FR) 2004-01-14 — — EP claimed
EP-1098641-A4 CHEMICALLY INDUCED INTRACELLULAR HYPERTHERMIA ST JUDE PHARMACEUTICALS INC (US) 2003-08-27 — — EP claimed
EP-1098641-A1 CHEMICALLY INDUCED INTRACELLULAR HYPERTHERMIA Texas Pharmaceuticals, Inc. (US) 2001-05-16 — — EP claimed
US-6054137-A A THERAPEUTIC TREATMENT FOR STIMULATING PROLIFERATION OF HUMAN KERATINOCYTES AND FOR SKIN DISORDERS SOCIETE L'OREAL S.A. (FR) 2000-04-25 — — US claimed
WO-2000006143-A1 CHEMICALLY INDUCED INTRACELLULAR HYPERTHERMIA TEXAS PHARMACEUTICALS, INC. (US) 2000-02-10 — — WO claimed
US-5807898-A ASPIDIN, DESASPIDIN, METHYLENEBISASPIDINOL KAPADIA GOVIND J (US) 1998-09-15 — — US claimed
WO-2026090318-A2 ENCAPSULATION COMPOSITIONS AND METHODS FOR ENCAPSULATING ACTIVE AGENTS DEFY-Tech Labs, Inc. (US) 2026-04-30 — — WO disclosed
US-20260108444-A1 ENCAPSULATION COMPOSITIONS AND METHODS FOR ENCAPSULATING ACTIVE AGENTS DEFY TECH LABS INC (US) 2026-04-23 — — US disclosed
US-20260081034-A1 SYSTEMS AND METHODS FOR MEASURING, LEARNING, AND USING EMERGENT PROPERTIES OF COMPLEX ADAPTIVE SYSTEMS EMERJA CORP (US) 2026-03-19 — — US disclosed
US-20260081035-A1 SYSTEMS AND METHODS FOR MEASURING, LEARNING, AND USING EMERGENT PROPERTIES OF COMPLEX ADAPTIVE SYSTEMS EMERJA CORP (US) 2026-03-19 — — US disclosed
WO-2025128952-A1 MANGANESE DOPED METAL ORGANIC FRAMEWORKS AND METHODS OF MAKING AND USE THEREOF BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-06-19 — — WO disclosed
US-20250161394-A1 Compositions Comprising Kavalactones NATURAL EXTRACTION SYS LLC (US) 2025-05-22 — — US disclosed
US-5807898-A ASPIDIN, DESASPIDIN, METHYLENEBISASPIDINOL KAPADIA GOVIND J (US) 1998-09-15 — — US disclosed
US-5807898-A ASPIDIN, DESASPIDIN, METHYLENEBISASPIDINOL KAPADIA GOVIND J (US) 1998-09-15 — — US disclosed
US-5684035-A NAPHTHOQUINONES KAPADIA GOVIND J (US) 1997-11-04 — — US disclosed
EP-0412211-A1 Cancer therapy system THERAPEUTICAL SYSTEMS CORPORATION (US) 1991-02-13 — — EP disclosed
US-4935450-A Cancer therapy system for effecting oncolysis of malignant neoplasms THERAPEUTICAL SYSTEMS CORPORATION (US) 1990-06-19 — — US disclosed
US-4724234-A ADMINISTERING NUTRITIONAL REGIMEN AND AGENTS WHICH UNCOUPLE OXIDATIVE PHOSPHORYLATION THERAPEUTICAL SYSTEMS CORP. (US) 1988-02-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260108444-A1 ENCAPSULATION COMPOSITIONS AND METHODS FOR ENCAPSULATING ACTIVE AGENTS LIPA, LIPC, ACACA FASN 87/4885MEN1 3824/4885KMT2A 2567/4885
US-20260081035-A1 SYSTEMS AND METHODS FOR MEASURING, LEARNING, AND USING EMERGENT PROPERTIES OF COMPLEX ADAPTIVE SYSTEMS PYGB, CRH, CRY1 FASN 2989/4885MEN1 1037/4885KMT2A 3027/4885
US-20260081034-A1 SYSTEMS AND METHODS FOR MEASURING, LEARNING, AND USING EMERGENT PROPERTIES OF COMPLEX ADAPTIVE SYSTEMS CRH, HCRTR1, PER2 FASN 2471/4885MEN1 2123/4885KMT2A 2802/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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