Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.34 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Desaspidin SCHEMBL29613713 | 0.90 | FASN (0.51) | FASNMEN1KMT2APAK1MAPT | |
| Desaspidin SCHEMBL2732746 | 0.90 | FASN (0.51) | FASNMEN1KMT2APAK1MAPT | |
| SCHEMBL29387296 | 0.80 | FASN (0.59) | FASNMEN1KMT2APAK1 | |
| SCHEMBL30212080 | 0.77 | FASN (0.66) | FASNMEN1KMT2APAK1MAPT | |
| SCHEMBL30212085 | 0.77 | FASN (0.66) | FASNMEN1KMT2APAK1CYP19A1 | |
| SCHEMBL8573383 | 0.75 | FASN (0.51) | FASNMEN1KMT2APAK1MAPT | |
| SCHEMBL4742082 | 0.74 | FASN (0.63) | FASN | |
| SCHEMBL155672 | 0.72 | FASN (0.48) | FASN | |
| SCHEMBL1785484 | 0.70 | FASN (0.60) | FASN | |
| SCHEMBL4962391 | 0.69 | FASN (0.64) | FASNALOX15HPGDALOX12SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103492389-B | Pyrazolo [4,3-d] pyrimidine as inhibitors of kinases | 原真股份有限公司 | 2016-09-14 | — | — | CN | disclosed |