Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 5/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | LSS | P48449 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MLNR | O43193 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8573952 | 0.68 | CHIT1 (0.35) | MAPKAPK2MLNR | |
| SCHEMBL8571349 | 0.68 | CHIT1 (0.34) | MAPKAPK2MLNR | |
| SCHEMBL6412306 | 0.64 | BMP1 (0.54) | CNR2MAPT | |
| Octane SCHEMBL10612108 | 0.64 | KCNH2 (0.51) | CNR2LSSKCNH2 | |
| SCHEMBL10669758 | 0.62 | LSS (0.62) | LSS | |
| SCHEMBL25420992 | 0.62 | GNAO1 (0.43) | MAPTTHRB | |
| SCHEMBL25253971 | 0.62 | GNAO1 (0.43) | MAPTTHRB | |
| SCHEMBL25420232 | 0.62 | GNAO1 (0.43) | MAPTTHRB | |
| SCHEMBL10464788 | 0.62 | GNAO1 (0.43) | MAPTTHRB | |
| SCHEMBL11620858 | 0.62 | HRH3 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716950-A | NONTOXIC ANTIALLERGEN AND ANTIASTHMATIC HAVING LOW ANTIHISTAMINIC SIDE EFFECTS | NIPPON SHOJI KABUSHIKI KAISHA (JP) | 1998-02-10 | — | — | US | disclosed |