Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 19/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL8574182 | 0.92 | ACHE (0.49) | ACHEMEN1KMT2ABCHE | |
| Fumaric Acid SCHEMBL8574186 | 0.92 | ACHE (0.49) | ACHEMEN1KMT2ABCHE | |
| SCHEMBL8569904 | 0.91 | ACHE (0.53) | ACHEMEN1KMT2ABCHE | |
| Maleic Acid SCHEMBL8572220 | 0.84 | ACHE (0.50) | ACHEMEN1KMT2ABCHE | |
| Fumaric Acid SCHEMBL8572224 | 0.84 | ACHE (0.50) | ACHEMEN1KMT2ABCHE | |
| SCHEMBL8574931 | 0.81 | ACHE (0.53) | ACHEMEN1KMT2ABCHE | |
| SCHEMBL8568157 | 0.79 | DRD4 (0.49) | ACHE | |
| SCHEMBL8573676 | 0.77 | ACHE (0.52) | ACHEMEN1KMT2A | |
| SCHEMBL13462879 | 0.73 | MEN1 (0.63) | ACHEMEN1KMT2A | |
| SCHEMBL10164221 | 0.72 | ACHE (0.62) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750542-A | Benzisoxazole and benzisothizole derivatives as cholinesterase inhibitors | PFIZER (US) | 1998-05-12 | — | — | US | disclosed |