Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | STAT1 | P42224 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8572275 | 0.81 | HDAC4 (0.37) | ALDH1A1LMNAMAPK1CYP1A2CYP2C19 | |
| SCHEMBL20051409 | 0.80 | CYP2C9 (0.46) | KDM4EALDH1A1LMNAMAPK1CYP2C19 | |
| SCHEMBL10274463 | 0.74 | PTGS1 (0.41) | ALDH1A1LMNAMAPK1CYP1A2CYP2C19 | |
| SCHEMBL8571428 | 0.74 | TSHR (0.53) | CA2KDM4EALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL11854767 | 0.74 | CYP1A2 (0.36) | CYP1A2CYP2C19CYP3A4CYP2C9 | |
| SCHEMBL9145627 | 0.74 | PTGS2 (0.46) | CA2KDM4EALDH1A1CYP3A4 | |
| SCHEMBL3525050 | 0.72 | ALDH1A1 (0.59) | CA2KDM4EALDH1A1LMNACYP1A2 | |
| SCHEMBL1395778 | 0.72 | CYP3A4 (0.68) | ALDH1A1LMNACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL28648226 | 0.72 | CYP3A4 (0.46) | KDM4EALDH1A1LMNACYP1A2CYP2C19 | |
| SCHEMBL10274494 | 0.72 | CNR1 (0.41) | KDM4EALDH1A1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846990-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB CO. (US) | 1998-12-08 | — | — | US | disclosed |