Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 7/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21565687 | 0.82 | ERCC1 (0.56) | SMN1; SMN2HPGDHSD17B10ALDH1A1MEN1 | |
| SCHEMBL8574152 | 0.80 | CA2 (0.43) | CYP2C9CYP2C19HPGDALDH1A1KDM4E | |
| SCHEMBL22114100 | 0.77 | APEX1 (0.61) | CYP2C19HPGDALDH1A1TDP1KDM4E | |
| SCHEMBL20051410 | 0.76 | CYP2C9 (0.46) | CYP2C9CYP2C19SMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL7322125 | 0.75 | SMN1; SMN2 (0.68) | SMN1; SMN2HPGDHSD17B10ALDH1A1TDP1 | |
| SCHEMBL8572275 | 0.74 | HDAC4 (0.37) | CYP2C9CYP2C19HPGDALDH1A1GAA | |
| SCHEMBL10274463 | 0.71 | PTGS1 (0.41) | CYP2C9CYP2C19SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL11854767 | 0.70 | CYP1A2 (0.36) | CYP2C9CYP2C19 | |
| SCHEMBL9145627 | 0.70 | PTGS2 (0.46) | ALDH1A1TDP1GAAKDM4E | |
| SCHEMBL8571428 | 0.70 | TSHR (0.53) | CYP2C9CYP2C19SMN1; SMN2HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11234914-B2 | Monosubstituted urea derivatives as a self-tanning substance | MERCK PATENT GMBH (DE) | 2022-02-01 | — | — | US | disclosed |
| EP-3522993-B1 | MONOSUBSTITUTED UREA DERIVATIVES AS A SELF-TANNING SUBSTANCE | MERCK PATENT GMBH (DE) | 2021-04-07 | — | — | EP | disclosed |
| US-20200038304-A1 | MONOSUBSTITUTED UREA DERIVATIVES AS A SELF-TANNING SUBSTANCE | MERCK PATENT GMBH (DE) | 2020-02-06 | — | — | US | disclosed |
| WO-2018065358-A1 | MONOSUBSTITUTED UREA DERIVATIVES AS A SELF-TANNING SUBSTANCE | MERCK PATENT GMBH (DE) | 2018-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11234914-B2 | Monosubstituted urea derivatives as a self-tanning substance | SLC14A1, TYR, UROD | CYP2C9 952/4885CYP2C19 456/4885SMN1; SMN2 4476/4885 |
| US-20200038304-A1 | MONOSUBSTITUTED UREA DERIVATIVES AS A SELF-TANNING SUBSTANCE | SLC14A1, TYR, UROD | CYP2C9 952/4885CYP2C19 456/4885SMN1; SMN2 4476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.