Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MC4R | P32245 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GSR | P00390 | 1/20 | 0.42 |
| ▸ | Q9HBH1 | 1/20 | 0.42 | |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11161912 | 0.84 | TDP1 (0.47) | MMP2TSHRCES1CA1CA2 | |
| Lysine SCHEMBL28385610 | 0.80 | GSR (0.56) | MMP2MC4RALDH1A1GSRGRM8 | |
| Lysine SCHEMBL28327845 | 0.80 | GSR (0.56) | MMP2MC4RALDH1A1GSRGRM8 | |
| SCHEMBL31661119 | 0.80 | MMP2 (0.48) | MMP2TSHRTDP1MC4RLMNA | |
| SCHEMBL2804606 | 0.79 | MMP2 (0.62) | MMP2LMNAGAAALDH1A1PDF | |
| SCHEMBL3670010 | 0.79 | MMP2 (0.62) | MMP2LMNAGAAALDH1A1PDF | |
| SCHEMBL4423862 | 0.79 | MMP2 (0.53) | MMP2MC4RGAAALDH1A1PDF | |
| SCHEMBL30358354 | 0.79 | MMP2 (0.53) | MMP2TSHRCA1CA2MC4R | |
| SCHEMBL8740500 | 0.79 | MMP2 (0.53) | MMP2MC4RGAAALDH1A1PDF | |
| Lysine SCHEMBL27760108 | 0.79 | GSR (0.54) | MMP2MC4RALDH1A1GSRGRM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817758-A | FOR PEPTIDES | TERRAPIN TECHNOLOGIES, INC. (US) | 1998-10-06 | — | — | US | disclosed |
| WO-1996040735-A1 | p-NITROBENZYL SIDE-CHAIN PROTECTION FOR SOLID-PHASE SYNTHESIS | TERRAPIN TECHNOLOGIES, INC. (US) | 1996-12-19 | — | — | WO | disclosed |