Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | BCL9 | O00512 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.40 |
| ▸ | Q9HBH1 | 1/20 | 0.40 | |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8740500 | 1.00 | MMP2 (0.53) | MMP2MAPTCRHBPCRHR2L3MBTL1 | |
| SCHEMBL2387943 | 1.00 | MMP2 (0.53) | MMP2MAPTCRHBPCRHR2L3MBTL1 | |
| SCHEMBL28783978 | 0.90 | MMP2 (0.49) | MMP2MAPTCRHBPCRHR2L3MBTL1 | |
| SCHEMBL9840744 | 0.82 | BCL9 (0.50) | MAPTCRHBPCRHR2L3MBTL1BCL9 | |
| SCHEMBL7275811 | 0.82 | BCL9 (0.50) | MAPTCRHBPCRHR2L3MBTL1BCL9 | |
| SCHEMBL28323255 | 0.81 | BCL9 (0.51) | MAPTCRHBPCRHR2BCL9CTNNB1 | |
| SCHEMBL712246 | 0.81 | MMP2 (0.46) | MMP2MAPTKMT2AALDH1A1 | |
| SCHEMBL18941468 | 0.81 | PDF (0.48) | MMP2MAPTCRHBPCRHR2L3MBTL1 | |
| SCHEMBL18941467 | 0.81 | PDF (0.48) | MMP2MAPTCRHBPCRHR2L3MBTL1 | |
| SCHEMBL9819573 | 0.81 | BCL9 (0.47) | MMP2MAPTCRHBPCRHR2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8337823-B2 | Modified macromolecule | STARPHARMA PTY LIMITED (AU) | 2012-12-25 | — | — | US | disclosed |
| US-20090324535-A1 | MODIFIED MACROMOLECULE | STARPHARMA PTY LTD (AU) | 2009-12-31 | — | — | US | disclosed |
| EP-1981512-A1 | MODIFIED MACROMOLECULE | Starpharma Pty Limited (AU) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007082331-A1 | MODIFIED MACROMOLECULE | STARPHARMA PTY LIMITED (AU) | 2007-07-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090324535-A1 | MODIFIED MACROMOLECULE | MRPL11, MAX, MRPL38 | MMP2 151/4885MAPT 1971/4885CRHBP 1160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.