Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTO1 | P78417 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.34 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.34 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.34 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 2/20 | 0.34 |
| ▸ | KCNJ6 | P48051 | 2/20 | 0.34 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8576591 | 0.90 | GSTO1 (0.43) | GSTO1MCL1KCNH2KMT2AMEN1 | |
| SCHEMBL8572915 | 0.87 | MCL1 (0.45) | GSTO1MCL1KMT2AMEN1LMNA | |
| SCHEMBL8571663 | 0.85 | NR1H2 (0.37) | SMN1; SMN2CFTRSOS1 | |
| SCHEMBL8577471 | 0.84 | CA2 (0.46) | KCNH2CFTRGAASOS1 | |
| SCHEMBL22499513 | 0.79 | GAA (0.42) | KCNH2KMT2AMEN1MAPK1SMN1; SMN2 | |
| SCHEMBL29385230 | 0.79 | GAA (0.42) | KCNH2KMT2AMEN1MAPK1SMN1; SMN2 | |
| SCHEMBL8571651 | 0.77 | KCNH2 (0.38) | MCL1KCNH2KMT2AL3MBTL1KCNJ6 | |
| SCHEMBL8578752 | 0.77 | TSHR (0.39) | MCL1KCNH2KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL8576439 | 0.77 | MCL1 (0.46) | GSTO1MCL1KMT2AMEN1LMNA | |
| SCHEMBL8576755 | 0.74 | TSHR (0.36) | MCL1KCNH2SMN1; SMN2L3MBTL1KCNJ6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849796-A | Ortho-substituted benzoil acid derivatives | MERCK PATENT GELSELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-12-15 | — | — | US | disclosed |