Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 5/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.37 |
| ▸ | SDHB | P21912 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 2/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8577471 | 0.88 | CA2 (0.46) | CFTRSOS1CA1CA2CA5A | |
| SCHEMBL8576511 | 0.85 | LMNA (0.35) | NR1H2NR1H3CA1CA2CA5A | |
| SCHEMBL8574378 | 0.85 | GSTO1 (0.36) | CFTRSOS1SMN1; SMN2 | |
| SCHEMBL8581861 | 0.81 | SDHB (0.33) | NR1H2NR1H3SDHBCFTRVCAM1 | |
| SCHEMBL8607990 | 0.79 | SLC9A1 (0.46) | SDHBKDM4EHSD17B10 | |
| SCHEMBL2968143 | 0.78 | SLC9A1 (0.42) | VCAM1CA1CA2CA5ACA9 | |
| SCHEMBL8573395 | 0.77 | SLC9A1 (0.53) | — | |
| SCHEMBL8583327 | 0.77 | CNR2 (0.36) | — | |
| SCHEMBL8585506 | 0.77 | SCN9A (0.37) | NR1H2NR1H3SDHBCFTRKDM4E | |
| SCHEMBL8584048 | 0.77 | CA2 (0.46) | CFTRCA1CA2CA5ACA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849796-A | Ortho-substituted benzoil acid derivatives | MERCK PATENT GELSELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-12-15 | — | — | US | disclosed |