Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GRM3 | Q14832 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5233789 | 0.88 | POLB (0.40) | POLBKMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL4434030 | 0.86 | ALDH1A1 (0.43) | PDK1POLBMEN1KMT2AMAPT | |
| SCHEMBL8574578 | 0.82 | MEN1 (0.48) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL7289702 | 0.82 | ALDH1A1 (0.42) | POLBNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL22319904 | 0.82 | PDK1 (0.37) | PDK1POLBMEN1KMT2ANPC1 | |
| SCHEMBL22366358 | 0.82 | PDK1 (0.37) | PDK1POLBMEN1KMT2ANPC1 | |
| SCHEMBL3655590 | 0.81 | POLB (0.44) | POLBKMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL3778464 | 0.81 | POLB (0.44) | POLBKMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL7289057 | 0.80 | PTGIR (0.37) | ALDH1A1CYP4F2CYP4A11GRM3 | |
| SCHEMBL5659807 | 0.80 | LSS (0.48) | POLBMEN1KMT2AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763436-A | ANTICOAGULANTS | HOFFMANN-LA ROCHE INC. (US) | 1998-06-09 | — | — | US | disclosed |