Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8574641 | 0.88 | PDK1 (0.43) | POLBKMT2AALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL3655590 | 0.84 | POLB (0.44) | POLBKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL3778464 | 0.84 | POLB (0.44) | POLBKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL3780673 | 0.83 | GAA (0.40) | POLBGAAKMT2AALDH1A1NPC1 | |
| SCHEMBL3780679 | 0.83 | GAA (0.40) | POLBGAAKMT2AALDH1A1NPC1 | |
| SCHEMBL4434030 | 0.83 | ALDH1A1 (0.43) | POLBKMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL22366358 | 0.82 | PDK1 (0.37) | POLBSPHK1KMT2AALDH1A1NPC1 | |
| SCHEMBL22319904 | 0.82 | PDK1 (0.37) | POLBSPHK1KMT2AALDH1A1NPC1 | |
| SCHEMBL6134733 | 0.80 | ALDH1A1 (0.38) | SPHK1KMT2AALDH1A1RAB9A | |
| SCHEMBL7288809 | 0.80 | PTGIR (0.37) | ALDH1A1CYP4F2CYP4A11GRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1764367-A1 | THIENOPYRIDINE DERIVATIVES | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |