Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10627589 | 0.91 | CTSL (0.35) | CTSKCTSSPREPCTSLTRPA1 | |
| SCHEMBL10633587 | 0.87 | EPHX2 (0.42) | CTSLCA2CA1CA7GAA | |
| SCHEMBL8576306 | 0.87 | EPHX2 (0.42) | CTSLCA2CA1CA7GAA | |
| SCHEMBL9781378 | 0.83 | KMT2A (0.40) | GAAIDO1EPHX2KMT2A | |
| SCHEMBL8577285 | 0.82 | CTSL (0.46) | CTSKCTSSCTSLCTSBCA2 | |
| SCHEMBL10631067 | 0.82 | CTSL (0.46) | CTSKCTSSCTSLCTSBCA2 | |
| SCHEMBL8695509 | 0.81 | IDO1 (0.41) | CTSKCTSSCTSLGAAKLK5 | |
| SCHEMBL9228941 | 0.80 | IDO1 (0.40) | CTSKCTSSCTSLCTSBGAA | |
| SCHEMBL6741998 | 0.80 | CTSK (0.42) | CTSKCTSSPREPCTSLTRPA1 | |
| SCHEMBL13869102 | 0.76 | CTSK (0.44) | CTSKCTSSPREPCTSLTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789386-A | WATER SOLUBLE ANTITUMOR AGENTS; INJECTABLE | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1998-08-04 | — | — | US | disclosed |
| EP-0374097-A2 | Use of peptide isosteres as retroviral protease inhibitors | CIBA-GEIGY AG (CH) | 1990-06-20 | — | — | EP | disclosed |
| EP-0374098-A2 | Inhibitors of retroviral proteases | CIBA-GEIGY AG (CH) | 1990-06-20 | — | — | EP | disclosed |
| EP-0295316-A2 | Antitumor amino acid and peptide derivatives of 1,4-bis[ (aminoalkyl and hydroxyaminoalkyl)- amino]-5,8 dihydroxyanthraquinones | AMERICAN CYANAMID COMPANY (US) | 1988-12-21 | — | — | EP | disclosed |
| US-4732970-A | Antitumor amino acid and peptide derivatives of 1,4-bis(aminoalkyl and hydroxy-aminoalkyl)amino)-5,8-dihydroxyanthraquinones | AMERICAN CYANAMID COMPANY (US) | 1988-03-22 | — | — | US | disclosed |