Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28757968 | 0.80 | ALDH1A1 (0.44) | KDM4EPKMALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL276275 | 0.79 | ALDH1A1 (0.62) | KDM4EPKMALDH1A1CYP1A2HPGD | |
| SCHEMBL8146643 | 0.78 | KDM4E (0.48) | KDM4EPKMALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL1552673 | 0.76 | ALDH1A1 (0.54) | KDM4EPKMALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL2444986 | 0.76 | ALDH1A1 (0.50) | KDM4EPKMALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL2624097 | 0.75 | KDM4E (0.42) | KDM4EPKMALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL2441749 | 0.75 | KDM4E (0.42) | KDM4EPKMALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL1540028 | 0.75 | ALDH1A1 (0.49) | KDM4EPKMALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL2444646 | 0.74 | L3MBTL1 (0.46) | KDM4EPKMALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL19185698 | 0.74 | KDM4E (0.41) | KDM4EPKMALDH1A1CYP1A2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811554-A | REACTING AN IMINOETHER WITH A HALOGENATING AGENT AND THIOUREA; USED IN MAKING NOVEL AZO DYES | AGFA-GEVAERT, N.V. (BE) | 1998-09-22 | — | — | US | claimed |
| EP-0687674-A1 | Preparation of 2-amino-4-alkoxythiazoles being negatively substituted in the 5 position | AGFA-GEVAERT N.V. (BE) | 1995-12-20 | — | — | EP | claimed |