Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS9 | O00182 | 1/20 | 0.44 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.44 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.44 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TYMP | P19971 | 7/20 | 0.36 |
| ▸ | NT5E | P21589 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ANTXR2 | P58335 | 2/20 | 0.35 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | HMGCR | P04035 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8574780 | 1.00 | LGALS9 (0.44) | LGALS9LGALS1LGALS3LGALS7; LGALS7BUSP2 | |
| SCHEMBL8576918 | 1.00 | LGALS9 (0.44) | LGALS9LGALS1LGALS3LGALS7; LGALS7BUSP2 | |
| SCHEMBL2511080 | 0.89 | PTPN1 (0.49) | LGALS9LGALS1LGALS3LGALS7; LGALS7BUSP2 | |
| SCHEMBL11194912 | 0.88 | NT5E (0.46) | LGALS9LGALS1LGALS3LGALS7; LGALS7BUSP2 | |
| SCHEMBL18241589 | 0.85 | PTPN1 (0.46) | LGALS9LGALS1LGALS3LGALS7; LGALS7BUSP2 | |
| SCHEMBL22033884 | 0.84 | TSHR (0.39) | KMT2ATSHRTYMPCA1CA2 | |
| SCHEMBL22033902 | 0.84 | TSHR (0.39) | KMT2ATSHRTYMPCA1CA2 | |
| SCHEMBL25029339 | 0.83 | USP2 (0.55) | LGALS9LGALS1LGALS3LGALS7; LGALS7BUSP2 | |
| SCHEMBL3651596 | 0.83 | USP2 (0.55) | LGALS9LGALS1LGALS3LGALS7; LGALS7BUSP2 | |
| SCHEMBL8653182 | 0.83 | USP2 (0.55) | LGALS9LGALS1LGALS3LGALS7; LGALS7BUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998016537-A1 | NOVEL COMPOUNDS | ASTRA AKTIEBOLAG (PUBL) (SE) | 1998-04-23 | — | — | WO | disclosed |