Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960730 | 0.89 | TP53 (0.48) | TP53CALM1TSHRALDH1A1IDO1 | |
| SCHEMBL9075638 | 0.79 | TP53 (0.50) | TP53CALM1TSHRALDH1A1IDO1 | |
| SCHEMBL476127 | 0.78 | PTGS1 (0.48) | TP53CALM1TSHRALDH1A1IDO1 | |
| Fluoride SCHEMBL28075258 | 0.76 | PTGS1 (0.47) | TP53CALM1TSHRALDH1A1IDO1 | |
| SCHEMBL16298659 | 0.74 | TP53 (0.43) | TP53CALM1TSHRALDH1A1IDO1 | |
| SCHEMBL8992235 | 0.72 | TP53 (0.42) | TP53CALM1TSHRALDH1A1IDO1 | |
| SCHEMBL41195 | 0.71 | CALM1 (0.50) | TP53CALM1TSHRALDH1A1IDO1 | |
| Fluoride SCHEMBL27669420 | 0.69 | CALM1 (0.47) | TP53CALM1TSHRALDH1A1IDO1 | |
| Ethylbenzene SCHEMBL1332452 | 0.67 | — | — | |
| Ethylbenzene SCHEMBL11223212 | 0.67 | TP53 (1.00) | TP53CALM1TSHRALDH1A1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4424343-A | Preparation of 1-N- ω-amino-α-hydroxyalkanoyl!kanamycin polysilylates and products | BRISTOL MYERS COMPANY (US) | 1984-01-03 | — | — | US | claimed |
| US-5808112-A | Preparation of cis-4-O-protected-2-cyclopentenol derivatives | HOECHST MARION ROUSSEL INC. (US) | 1998-09-15 | — | — | US | disclosed |
| CN-1179770-A | Preparation of cis- 4 -0 -protected -2 -cyclopentenol derivatives | HOECHST MARION ROUSSEL INC (US) | 1998-04-22 | — | — | CN | disclosed |
| US-5728899-A | Preparation of cis-4-O-protected-2-cyclopentenol derivatives | HOECHST MARION ROUSSEL INC. (US) | 1998-03-17 | — | — | US | disclosed |
| EP-0817764-A1 | PREPARATION OF CIS-4-O-PROTECTED-2-CYCLOPENTENOL DERIVATIVES | HOECHST MARION ROUSSEL, INC. (US) | 1998-01-14 | — | — | EP | disclosed |
| WO-1996030320-A1 | PREPARATION OF CIS-4-O-PROTECTED-2-CYCLOPENTENOL DERIVATIVES | HOECHST MARION ROUSSEL, INC. (US) | 1996-10-03 | — | — | WO | disclosed |