Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 3/20 | 0.33 |
| ▸ | ELANE | P08246 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6737901 | 0.74 | ELANE (0.40) | TLR8TLR7DPP4ELANE | |
| SCHEMBL5509029 | 0.70 | TLR8 (0.33) | TLR8TLR7 | |
| SCHEMBL5510125 | 0.70 | ELANE (0.39) | DPP4ELANE | |
| SCHEMBL18268482 | 0.68 | TLR7 (0.41) | TLR8TLR7RAB9AADORA3ADORA2A | |
| SCHEMBL4763415 | 0.66 | TLR7 (0.49) | TLR8TLR7 | |
| Hydrochloric Acid SCHEMBL10970517 | 0.64 | MAOB (0.50) | RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8575152 | 0.64 | JAK2 (0.41) | TLR8TLR7ADORA3 | |
| SCHEMBL5032885 | 0.64 | ELANE (0.43) | TLR8TLR7DPP4ELANEADORA2A | |
| SCHEMBL4586839 | 0.64 | TLR7 (0.38) | TLR8TLR7ADORA3ADORA2AADORA2B | |
| SCHEMBL4065218 | 0.64 | ADORA1 (0.36) | TLR7ADORA3ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685129-A4 | OXIME SUBSTITUTED IMIDAZO RING COMPOUNDS | 3M INNOVATIVE PROPERTIES CO (US) | 2008-10-22 | — | — | EP | disclosed |
| EP-1685129-A2 | OXIME SUBSTITUTED IMIDAZO RING COMPOUNDS | 3M Innovative Properties Company (US) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005048933-A2 | OXIME SUBSTITUTED IMIDAZO RING COMPOUNDS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-06-02 | — | — | WO | disclosed |