Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8575244 | 0.84 | ALDH1A1 (0.36) | KDM4ESMN1; SMN2ALDH1A1PDE4APDE4B | |
| SCHEMBL8577182 | 0.83 | GPR35 (0.36) | KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL8578476 | 0.79 | OPRM1 (0.35) | KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL8575948 | 0.77 | SMN1; SMN2 (0.34) | KDM4ESMN1; SMN2ALDH1A1CYP3A4MEN1 | |
| SCHEMBL8576908 | 0.75 | KDM4E (0.42) | KDM4ESMN1; SMN2ALDH1A1PDE4DCYP3A4 | |
| SCHEMBL8578670 | 0.75 | KMT2A (0.41) | KDM4ESMN1; SMN2ALDH1A1CYP3A4MEN1 | |
| SCHEMBL8577175 | 0.74 | GPR35 (0.36) | KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL8578006 | 0.73 | ACACB (0.33) | KDM4ESMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL8575820 | 0.73 | ACACB (0.35) | KDM4ESMN1; SMN2ALDH1A1PDE4APDE4B | |
| SCHEMBL8577363 | 0.72 | MEN1 (0.34) | KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719310-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-02-17 | — | — | US | disclosed |
| US-5610122-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-03-11 | — | — | US | disclosed |