Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 12/20 | 0.67 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.47 |
| ▸ | HTR5A | P47898 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8031307 | 0.87 | MTNR1A (0.86) | MTNR1AMTNR1BSMN1; SMN2MAPTNPC1 | |
| SCHEMBL1924859 | 0.81 | MTNR1A (0.79) | MTNR1AMTNR1BMAPT | |
| SCHEMBL8883537 | 0.80 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL8883384 | 0.79 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL8881811 | 0.79 | MTNR1A (0.89) | MTNR1AMTNR1B | |
| SCHEMBL8037709 | 0.79 | MTNR1A (0.56) | MTNR1AMTNR1BHTR5A | |
| SCHEMBL8884045 | 0.79 | MTNR1A (1.00) | MTNR1AMTNR1BMAPT | |
| SCHEMBL8605628 | 0.78 | MTNR1A (0.59) | MTNR1AMTNR1BHTR5ASMN1; SMN2POLB | |
| SCHEMBL10224643 | 0.77 | MTNR1A (0.62) | MTNR1AMTNR1BHTR5A | |
| SCHEMBL8882361 | 0.76 | MTNR1A (0.74) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760071-A | AN UREA OR THIOUREA COMPOUNDS FOR TREATING MELATONINERGIC SYSTEM DISORDER, SLEEP DISORDER | ADIR ET COMPAGNIE (FR) | 1998-06-02 | — | — | US | disclosed |
| US-5731352-A | THERAPY FOR DISORDERS OF THE MELATONINERGIC SYSTEM | ADIR ET COMPAGNIE (FR) | 1998-03-24 | — | — | US | disclosed |