Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 8/20 | 0.56 |
| ▸ | HTR5A | P47898 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8431821 | 0.91 | MTNR1A (0.59) | MTNR1AHTR5ACYP2A6HTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL8882742 | 0.89 | MTNR1A (0.58) | MTNR1AHTR5ACYP2A6HTR1AHTR1D | |
| SCHEMBL10224643 | 0.82 | MTNR1A (0.62) | MTNR1AHTR5ACYP2A6MTNR1BCA2 | |
| SCHEMBL8030991 | 0.81 | CA2 (0.54) | MTNR1AHTR5ACYP2A6HTR1DTAAR1 | |
| SCHEMBL8431972 | 0.81 | HTR1A (0.53) | MTNR1AHTR5ACYP2A6HTR1AHTR1D | |
| SCHEMBL8435762 | 0.80 | HTR5A (0.54) | MTNR1AHTR5ACYP2A6HTR1AHTR1D | |
| SCHEMBL8575255 | 0.79 | MTNR1A (0.67) | MTNR1AHTR5AMTNR1B | |
| SCHEMBL8434421 | 0.78 | HTR1A (0.56) | MTNR1AHTR5ACYP2A6HTR1AHTR1D | |
| SCHEMBL5237109 | 0.78 | CYP2A6 (0.71) | CYP2A6CA2 | |
| SCHEMBL5234280 | 0.78 | MTNR1A (0.55) | MTNR1AHTR5ACYP2A6HTR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745586-B1 | Aryl(alkyl) propylamides, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-03-08 | — | — | EP | disclosed |
| EP-0745586-A1 | Aryl(alkyl) propylamides, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-12-04 | — | — | EP | disclosed |