Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.35 |
| ▸ | GCK | P35557 | 2/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8415393 | 0.84 | DPP4 (0.40) | ALDH1A1SMN1; SMN2ITGB3ITGA2B | |
| SCHEMBL8575282 | 0.82 | TDP1 (0.36) | HRH3ALDH1A1SMN1; SMN2GCK | |
| Hydrochloric Acid SCHEMBL8415510 | 0.80 | FFAR4 (0.40) | ITGB3ITGA2B | |
| Hydrochloric Acid SCHEMBL9409381 | 0.76 | HRH3 (0.44) | HRH3EPHX2ALDH1A1SMN1; SMN2ITGB3 | |
| SCHEMBL3859776 | 0.75 | MEN1 (0.36) | ALDH1A1ADRB2 | |
| SCHEMBL8574007 | 0.75 | ITGB3 (0.39) | HRH3EPHX2ITGB3ITGA2B | |
| SCHEMBL8415391 | 0.74 | NPC1 (0.38) | ALDH1A1 | |
| SCHEMBL3860582 | 0.74 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL8576047 | 0.74 | HRH3 (0.38) | HRH3EPHX2GCK | |
| SCHEMBL8417066 | 0.74 | ITGB3 (0.48) | HRH3ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |