Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GCK | P35557 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8415391 | 0.82 | NPC1 (0.38) | KDM4EALDH1A1TSHR | |
| SCHEMBL8575284 | 0.82 | HRH3 (0.41) | GCKHRH3ALDH1A1SMN1; SMN2 | |
| SCHEMBL6910863 | 0.78 | SLC6A2 (0.50) | TDP1SLC6A2SLC6A4SLC6A3POLB | |
| Hydrochloric Acid SCHEMBL1660306 | 0.77 | HTR2C (0.50) | TDP1SLC6A2SLC6A4SLC6A3POLB | |
| SCHEMBL8417064 | 0.72 | ITGB3 (0.43) | KDM4EALDH1A1 | |
| SCHEMBL8575545 | 0.71 | P2RX3 (0.34) | TDP1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4049067 | 0.71 | KDM1A (0.40) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8575389 | 0.70 | GAA (0.35) | TDP1GCKKDM4EALDH1A1HPGD | |
| SCHEMBL4610243 | 0.69 | SLC18A3 (0.44) | SLC6A2SLC6A4HPGDSMN1; SMN2 | |
| SCHEMBL3815926 | 0.69 | SLC18A3 (0.44) | SLC6A2SLC6A4HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |