Sugi Predict

Sugi Predict / Compounds / SCHEMBL3626322

SCHEMBL3626322

SCHEMBL3626322

CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 2/20 0.38
▸ MEN1 O00255 1/20 0.36
▸ GAA P10253 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ TET2 Q6N021 3/20 0.35
▸ KDM4A O75164 2/20 0.35
▸ KDM4C Q9H3R0 2/20 0.35
▸ KDM2A Q9Y2K7 2/20 0.35
▸ TET3 O43151 1/20 0.35
▸ HDAC6 Q9UBN7 2/20 0.35
▸ HDAC1 Q13547 1/20 0.35
▸ HDAC2 Q92769 1/20 0.35
▸ FOLH1 Q04609 4/20 0.34
▸ GABRP O00591 2/20 0.34
▸ GABRD O14764 2/20 0.34
▸ GABRA1 P14867 2/20 0.34
▸ GABRB1 P18505 2/20 0.34
▸ GABRG2 P18507 2/20 0.34
▸ GABRB3 P28472 2/20 0.34
▸ GABRA5 P31644 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26129393 1.00 CYP1A2 (0.38) CYP1A2MEN1GAAKMT2ATET2
SCHEMBL26129394 1.00 CYP1A2 (0.38) CYP1A2MEN1GAAKMT2ATET2
SCHEMBL20514701 0.90 MEN1 (0.37) CYP1A2MEN1GAAKMT2AHDAC6
SCHEMBL20514700 0.90 MEN1 (0.37) CYP1A2MEN1GAAKMT2AHDAC6
SCHEMBL13007473 0.88 HDAC6 (0.34) CYP1A2MEN1GAAKMT2ATET2
SCHEMBL8575312 0.88 CYP1A2 (0.33) CYP1A2MEN1GAAKMT2ATET2
SCHEMBL8575315 0.88 CYP1A2 (0.33) CYP1A2MEN1GAAKMT2ATET2
SCHEMBL14150478 0.87 HDAC1 (0.41) MEN1GAAKMT2AHDAC6HDAC1
SCHEMBL8764441 0.87 KMT2A (0.39) MEN1GAAKMT2AHDAC6HDAC1
SCHEMBL30180302 0.85 CA12 (0.34) CYP1A2MEN1GAAKMT2AHDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250162987-A1 PREPARATION OF GAMMA-GLUTAMYLCYSTEINE, A PRECURSOR OF GLUTATHIONE CHILDREN'S NATIONAL MEDICAL CENTER (US) 2025-05-22 — — US claimed
WO-2023196276-A1 PREPARATION OF GAMMA L-GLUTAMYL L-CYSTEINE AND BIS GAMMA L-GLUTAMYL CYCSTINE CHILDREN'S NATIONAL MEDICAL CENTER (US) 2023-10-12 — — WO claimed
US-20250162987-A1 PREPARATION OF GAMMA-GLUTAMYLCYSTEINE, A PRECURSOR OF GLUTATHIONE CHILDREN'S NATIONAL MEDICAL CENTER (US) 2025-05-22 — — US disclosed
WO-2023196276-A1 PREPARATION OF GAMMA L-GLUTAMYL L-CYSTEINE AND BIS GAMMA L-GLUTAMYL CYCSTINE CHILDREN'S NATIONAL MEDICAL CENTER (US) 2023-10-12 — — WO disclosed
EP-3923724-B1 HERBICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2023-07-26 — — EP disclosed
US-11618743-B2 Herbicidal compounds SYNGENTA PARTICIPATIONS AG (CH) 2023-04-04 — — US disclosed
US-20220192195-A1 HERBICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2022-06-23 — — US disclosed
US-20220159956-A1 HERBICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2022-05-26 — — US disclosed
US-20220142162-A1 HERBICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2022-05-12 — — US disclosed
US-20220125051-A1 PRE-HARVEST DESICCATION METHOD SYNGENTA CROP PROTECTION AG (CH) 2022-04-28 — — US disclosed
US-20220125052-A1 Herbicidal Compositions SYNGENTA CROP PROTECTION AG (CH) 2022-04-28 — — US disclosed
WO-2020164971-A1 PRE-HARVEST DESICCATION METHOD SYNGENTA CROP PROTECTION AG (CH) 2020-08-20 — — WO disclosed
WO-2020164924-A1 HERBICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2020-08-20 — — WO disclosed
WO-2020164920-A1 HERBICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2020-08-20 — — WO disclosed
EP-3668855-A1 HERBICIDAL COMPOUNDS Syngenta Participations AG (CH) 2020-06-24 — — EP disclosed
WO-2019034757-A1 HERBICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2019-02-21 — — WO disclosed
EP-2203420-A1 HIV PROTEASE INHIBITORS Merck Sharp & Dohme Corp. (US) 2010-07-07 — — EP disclosed
US-20100093811-A1 HIV PROTEASE INHIBITORS MERCK SHARP & DOHME CORP. 2010-04-15 — — US disclosed
WO-2009042094-A2 HIV PROTEASE INHIBITORS MERCK & CO., INC. (US) 2009-04-02 — — WO disclosed
WO-2009042093-A1 HIV PROTEASE INHIBITORS MERCK & CO., INC. (US) 2009-04-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220142162-A1 HERBICIDAL COMPOSITIONS PPOX, DDT, HPD CYP1A2 58/4885MEN1 4663/4885GAA 500/4885
US-20220159956-A1 HERBICIDAL COMPOSITIONS DDT, HPD, DHFR CYP1A2 5/4885MEN1 4649/4885GAA 571/4885
US-20100093811-A1 HIV PROTEASE INHIBITORS PRSS1, FURIN, SERPINB1 CYP1A2 728/4885MEN1 2771/4885GAA 207/4885
US-11618743-B2 Herbicidal compounds DDT, ACHE, GSTO1 CYP1A2 41/4885MEN1 3365/4885GAA 160/4885
US-20220125052-A1 Herbicidal Compositions DDT, HPD, DHFR CYP1A2 19/4885MEN1 4524/4885GAA 930/4885
US-20220125051-A1 PRE-HARVEST DESICCATION METHOD GMDS, TREH, DAD1 CYP1A2 2850/4885MEN1 2047/4885GAA 452/4885
US-20250162987-A1 PREPARATION OF GAMMA-GLUTAMYLCYSTEINE, A PRECURSOR OF GLUTATHIONE GCLC, GGCT, GGT1 CYP1A2 1741/4885MEN1 2820/4885GAA 756/4885
US-20220192195-A1 HERBICIDAL COMPOSITIONS GLO1, LCT, HACL2 CYP1A2 366/4885MEN1 4827/4885GAA 34/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.