Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | PTGES | O14684 | 4/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | NDUFS8 | O00217 | 1/20 | 0.47 |
| ▸ | COXFA4 | O00483 | 1/20 | 0.47 |
| ▸ | NDUFAB1 | O14561 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8575335 | 1.00 | MAOB (0.53) | MAOBMAOAPTGESALOX15MTNR1A | |
| SCHEMBL15702174 | 0.99 | PTGES (0.54) | MAOBMAOAPTGESALOX15MTNR1A | |
| SCHEMBL6072534 | 0.89 | TRPV1 (0.56) | ALOX15TRPV1 | |
| SCHEMBL12070045 | 0.88 | ALDH1A1 (0.51) | PTGES | |
| SCHEMBL31438944 | 0.87 | ICMT (0.56) | PTGESALOX15MTNR1ATRPV1 | |
| SCHEMBL6653805 | 0.87 | ICMT (0.56) | PTGESALOX15MTNR1ATRPV1 | |
| SCHEMBL7033631 | 0.87 | ICMT (0.56) | PTGESALOX15MTNR1ATRPV1 | |
| SCHEMBL6652681 | 0.87 | ICMT (0.56) | PTGESALOX15MTNR1ATRPV1 | |
| SCHEMBL31438947 | 0.87 | ICMT (0.56) | PTGESALOX15MTNR1ATRPV1 | |
| SCHEMBL15756532 | 0.86 | ICMT (0.58) | PTGESALOX15MTNR1ATRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849930-A | Pyrazolidine derivative radical scavenger brain-infarction depressant and brain-edema depressant | SHISEIDO CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |