Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9196797 | 0.87 | SLC9A1 (0.66) | SLC9A1SMN1; SMN2GAAKDM4EHSD17B10 | |
| SCHEMBL11768216 | 0.86 | KDM4E (0.47) | SLC9A1HTR6SMN1; SMN2GAAKDM4E | |
| SCHEMBL9436719 | 0.86 | SLC9A1 (0.68) | SLC9A1SMN1; SMN2GAAKDM4EHSD17B10 | |
| SCHEMBL11718138 | 0.85 | ALDH1A1 (0.45) | HTR6SMN1; SMN2GAAKDM4EHSD17B10 | |
| SCHEMBL22542102 | 0.80 | ALDH1A1 (0.54) | HTR6ALDH1A1 | |
| SCHEMBL2303906 | 0.80 | HSD17B10 (0.55) | HTR6GAAKDM4EHSD17B10POLB | |
| SCHEMBL615633 | 0.78 | KDR (0.48) | HTR6 | |
| SCHEMBL2557226 | 0.78 | USP2 (0.54) | HTR6USP2ALDH1A1 | |
| SCHEMBL2307303 | 0.78 | ADRB1 (0.50) | HTR6GAAKDM4EHSD17B10POLB | |
| SCHEMBL27950425 | 0.78 | MYC (0.51) | HTR6GAAKDM4EHSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5783576-A | Benzoyl guanidine derivatives, the preparation thereof and their use in pharmaceutical compositions | BOEHRINGER INGELHEIM KG (DE) | 1998-07-21 | — | — | US | disclosed |