Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CXCR1 | P25024 | 8/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8579523 | 0.99 | MAPT (0.51) | MAPTALDH1A1HTTCXCR1CHRM2 | |
| SCHEMBL4311394 | 0.88 | MEN1 (0.45) | MAPTALDH1A1HTTCHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL8577214 | 0.86 | DRD2 (0.56) | MAPTCXCR1SMN1; SMN2DRD2DRD4 | |
| SCHEMBL8576630 | 0.85 | ALDH1A1 (0.66) | MAPTALDH1A1HTTCXCR1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8575375 | 0.84 | ALDH1A1 (0.65) | MAPTALDH1A1HTTCXCR1HDAC3 | |
| SCHEMBL13616475 | 0.82 | HDAC3 (0.43) | MAPTALDH1A1HTTCHRM2CHRM4 | |
| SCHEMBL38656805 | 0.82 | ALDH1A1 (0.54) | MAPTALDH1A1HTTCXCR1HDAC3 | |
| SCHEMBL1221707 | 0.81 | CHKA (0.51) | MAPTALDH1A1HTTCXCR1DRD2 | |
| SCHEMBL30930756 | 0.78 | DRD2 (0.48) | MAPTALDH1A1HTTCXCR1DRD2 | |
| SCHEMBL26952641 | 0.77 | DRD2 (0.45) | ALDH1A1SIGMAR1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998015541-A1 | NOVEL ISOXAZOL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND A PROCESS FOR THE PREPARATION OF THE NOVEL COMPOUNDS | EGIS Gyógyszergyár Rt. (HU) | 1998-04-16 | — | — | WO | disclosed |