SCHEMBL38656805

SCHEMBL38656805

CONc1ccc(-c2cc(CN3CCN(C)CC3)on2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.54
MAPT P10636 1/20 0.54
HTT P42858 1/20 0.54
HDAC3 O15379 1/20 0.46
HDAC4 P56524 1/20 0.46
HDAC1 Q13547 1/20 0.46
HDAC7 Q8WUI4 1/20 0.46
HDAC2 Q92769 1/20 0.46
HDAC10 Q969S8 1/20 0.46
HDAC11 Q96DB2 1/20 0.46
HDAC8 Q9BY41 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
HDAC9 Q9UKV0 1/20 0.46
HDAC5 Q9UQL6 1/20 0.46
CXCR1 P25024 8/20 0.44
CYP1A2 P05177 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
DRD2 P14416 4/20 0.40
DRD4 P21917 4/20 0.40
DRD3 P35462 4/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8576630 0.84 ALDH1A1 (0.66) ALDH1A1MAPTHTTCXCR1CYP1A2
Hydrochloric Acid SCHEMBL8575375 0.83 ALDH1A1 (0.65) ALDH1A1MAPTHTTHDAC3HDAC4
SCHEMBL8575432 0.82 MAPT (0.52) ALDH1A1MAPTHTTHDAC3HDAC4
Hydrochloric Acid SCHEMBL8579523 0.81 MAPT (0.51) ALDH1A1MAPTHTTHDAC3HDAC4
Hydrochloric Acid SCHEMBL8577214 0.80 DRD2 (0.56) MAPTCXCR1SMN1; SMN2DRD2DRD4
SCHEMBL30930756 0.77 DRD2 (0.48) ALDH1A1MAPTHTTCXCR1DRD2
SCHEMBL1221707 0.75 CHKA (0.51) ALDH1A1MAPTHTTCXCR1DRD2
SCHEMBL7452454 0.74 SMN1; SMN2 (0.50) ALDH1A1MAPTHTTCYP1A2SMN1; SMN2
SCHEMBL4320442 0.73 MAPT (0.53) ALDH1A1MAPTHTTHDAC3HDAC4
SCHEMBL30930754 0.73 SIRT6 (0.50) ALDH1A1MAPTHTTDRD2DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036715-A 2, 4-Diarylaminopyrimidine derivative containing benzodithioryl, and pharmaceutical composition and application thereof 盐城工业职业技术学院 2026-05-15 CN disclosed