Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | CPB1 | P15086 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8575501 | 0.88 | PTGER3 (0.35) | PTGER3PTGER2FFAR4S1PR1HDAC1 | |
| Hydrochloric Acid SCHEMBL8573491 | 0.88 | CTSG (0.39) | HDAC1HDAC8HDAC6NTRK1 | |
| SCHEMBL8575092 | 0.78 | CTSG (0.43) | — | |
| Hydrochloric Acid SCHEMBL8575626 | 0.77 | CTSG (0.42) | — | |
| SCHEMBL8575529 | 0.75 | PTGER4 (0.37) | PTGER3PTGER2MEN1KMT2AFFAR4 | |
| SCHEMBL8573886 | 0.73 | HDAC1 (0.40) | HDAC1HDAC8HDAC6 | |
| SCHEMBL8572958 | 0.73 | GRIN1 (0.40) | PTPN1 | |
| SCHEMBL7275491 | 0.72 | S1PR1 (0.52) | MEN1NPC1RAB9AKMT2AFFAR4 | |
| SCHEMBL8572789 | 0.72 | PTGER4 (0.40) | — | |
| SCHEMBL8573785 | 0.72 | FFAR4 (0.39) | PTGER3PTGER2MEN1KMT2AFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |