Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.31 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.31 |
| ▸ | CTSG | P08311 | 1/20 | 0.31 |
| ▸ | CMA1 | P23946 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8572815 | 0.91 | HTR7 (0.38) | PTGER4HTR7PPARGPPARDPPARA | |
| SCHEMBL8575501 | 0.84 | PTGER3 (0.35) | PPARDPPARAFFAR4TP53PTGER3 | |
| SCHEMBL8571536 | 0.77 | CASP3 (0.38) | ALDH1A1GAAMAPTCTSGCMA1 | |
| SCHEMBL8575092 | 0.76 | CTSG (0.43) | ALDH1A1GAATP53CTSGCMA1 | |
| SCHEMBL8575472 | 0.75 | PTGER3 (0.38) | PPARDPPARAFFAR4PTGER3PTGER2 | |
| Hydrochloric Acid SCHEMBL8575626 | 0.75 | CTSG (0.42) | ALDH1A1GAATP53CTSGCMA1 | |
| SCHEMBL8571508 | 0.75 | HTR7 (0.37) | HTR7OPRM1MAPTCTSGCMA1 | |
| SCHEMBL8573785 | 0.74 | FFAR4 (0.39) | PTGER4OPRM1OPRD1OPRK1FFAR4 | |
| SCHEMBL7282936 | 0.71 | S1PR1 (0.46) | PPARDPPARAFFAR4ALDH1A1GAA | |
| SCHEMBL8572789 | 0.70 | PTGER4 (0.40) | PTGER4ALDH1A1GAAFFAR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |